Quick Answer: Best Collagen Supplements
- Collagen Peptides Powder by Sports Research
- Collagen Peptides Powder by Physician’s Choice
- NeoCell Super Collagen + C
- Collagen Gummies Supplement by Mav Nutrition
- Collagen Peptides Packets by AMANDEAN
- Bulksupplements Hydrolyzed Collagen
- Zint Collagen Peptides Powder
- Youtheory – Collagen Advanced Formula
- Collagen Wrinkle Formula by Sanar Naturals
Collagen by Sports Research
[amazon fields="B00XQ2XGAA" value="thumb" image_size="medium" image_align="center"]- Quick and effective results
- No Unappealing Aftertaste
- Blends easily in liquid intakes
Collagen by Physician's Choice
[amazon fields="B07BB1VV9K" value="thumb" image_size="medium" image_align="center"]- Blend is Absorbing and Potent
- Blends easily in liquid intakes
- Quick and noticeable result
NeoCell Super Collagen + C
[amazon fields="B00028NF84" value="thumb" image_size="medium" image_align="center"]- Value for money
- Non-GMO and Gluten-free
- No Unappealing Aftertaste
Collagens are a family of triple helical proteins which carry out a wide range of functions within the human body.
These functions include tissue scaffolding, morphogenesis and repair, cell adhesion and migration, angiogenesis, etc.
Collagen is present in the extracellular matrix of vertebrate tissues such as the cartilage, bone and skin as elongated fibrils and in the basement membranes like in the glomerulus of the kidney where it plays a role in molecular filtration.
Recent studies have shown the presence of collagen on a few cell surfaces. Apart from this, a few collagens are also known to be precursors of certain bioactive peptides that are known to have paracrine functions.
Reviews of the Best Collagen Supplements
Collagen Peptides Powder by Sports Research
[amazon fields="B00XQ2XGAA" value="thumb" image_size="large" image_align="center"]Sports Research, established in 1980 in California, USA, is a family-owned company spearheading the manufacturing of health and wellness products.
The dietary supplement is available in the form of a powder-mix with net weight 454 g and serving size of 1 scoop (11.07 g). The servings per container amount to 41.
The supplement facts in each serving are:
- Hydrolyzed bovine collagen peptides – 11 g
- Sodium – 60 mg
- Protein – 10 g
The product is keto certified and gluten-free.
Some of the key USPs of the product are:
- High potent blend for effective performance
- Non-GMO verified and manufactured in cGMP facilities
- Third-party tested by Paleo & Keto Foundation
The Key Nutrients of the Supplements are :
Here are key Pros and Cons based on Analysis of Customer Reviews-
- Quick and effective results for most consumers
- Most found the ingredient blend potent and satisfying
- Blends easily in liquid intakes
- Most consumers experienced no unappealing aftertaste
- A few consumers reported inconsistent batch size and quality
- A few consumers found the product expensive to similar supplements
- A few consumers experienced digestive issues and allergic reactions
Collagen Peptides Powder by Physician's Choice
[amazon fields="B07BB1VV9K" value="thumb" image_size="large" image_align="center"]Physician’s Choice, established in Colorado, USA, is a manufacturer of supplements and clinically tested ingredients.
The dietary supplement is available in the form of a powder-mix with net weight 212 g and serving size of 1 scoop (7 g). The servings per container amount to 30.
The supplement facts in each serving are:
- Collagen Hydrolyzed Bovine digestive enzyme blend – 7000 mg
- Protein – 6 g
- The product is manufactured in a cGMP facility.
Some of the key USPs of the product are:
- Double hydrolyzed collagen and digestive enzymes for enhanced absorption
- Non-GMO, grass-fed and manufactured in cGMP facilities
- Third-party tested with ingredients of professional grade
The Key Nutrients of the Supplements are :
Here are key Pros and Cons based on Analysis of Customer Reviews-
- Quick and noticeable improvements for most consumers
- Most found the ingredient blend absorbing, potent and satisfying
- Blends easily in liquid intakes
- Easy to use with no unappealing aftertaste for most consumers
- A few consumers reported inconsistent batch size and taste
- A few consumers found that batch size is small for the price
- A few consumers experienced digestive issues and allergic reactions
NeoCell Super Collagen + C
[amazon fields="B00028NF84" value="thumb" image_size="large" image_align="center"]Neocell, established in 1988, is a manufacturer of collagen supplements and clinically tested ingredients.
The dietary supplement is available in the form of 120 tablets and serving size of 6. The servings per container amount to 20.
The supplement facts in each serving are:
- BioActive Neocell Collagen – 6000 mg
- Protein – 6 g
- Sodium – 30 mg
- Vitamin C – 60 mg
The product is manufactured in a non-GMO and gluten-free.
Some of the key USPs of the product are:
- Advanced hydrolyzation for enhanced bioavailability
- Potent combination of Types 1 & 3 hydrolyzed collagen peptides
- Non-GMO, gluten-free and no artificial flavors
The Key Nutrients of the Supplements are :
Here are key Pros and Cons based on Analysis of Customer Reviews-
- Quick and noticeable improvements for most consumers
- Most found the ingredient blend potent and satisfying
- Most consumers experienced no unappealing aftertaste
- Value for money
- A few consumers experienced no effects
- A few consumers found it difficult to swallow the tablets
- A few consumers experienced side effects
Collagen Gummies Supplement by Mav Nutrition
[amazon fields="B07DM3MBCS" value="thumb" image_size="large" image_align="center"]Mav Nutrition is a manufacturer of health and wellness products to meet the dietary needs of consumers.
The dietary supplement is available in the form of 60 gummies and serving size of 2. The servings per container amount to 30.
The supplement facts in each serving are:
- Hydrolyzed Collagen – 50 mg
- Selenium – 55 mcg
- Zinc – 5 mg
- Biotin – 3000 mcg
- Vitamin E – 14 mg
- Vitamin C – 80 mg
Some of the key USPs of the product are:
- Extra strength hydrolyzed collagen Type 1&3 with vitamins and minerals
- Includes key nutrients such as Vitamin C, E and Biotin
- Non-GMO, no gelatin and no artificial flavors
The Key Nutrients of the Supplements are :
Here are key Pros and Cons based on Analysis of Customer Reviews-
- Noticeable improvements for most consumers
- Easy to take and chew gummies compared to powder-mixes
- Most consumers found the taste and flavor appealing
- Value for money
- A few consumers experienced no noticeable impact
- A few consumers found the quality inconsistent
- A few consumers experienced side effects
Collagen Peptides Packets by AMANDEAN
[amazon fields="B01FUY7WAQ" value="thumb" image_size="large" image_align="center"]Amandean is a manufacturer of health and nutritional supplements, vitamins and superfoods to meet the dietary needs and requirements of consumers.
The dietary supplement is available in the form of a powder-mix with net weight 1 kg and serving size of 1 scoop (10 g). The servings per container amount to 100.
The supplement facts in each serving are:
- Hydrolyzed Collagen – 10 g
- Sodium – 55 mg
- Protein – 9 g
- The product is gluten-free, non-GMO and entirely natural.
Some of the key USPs of the product are:
- 90% + Collagen protein with 18 amino acids for best results
- Non-GMO, gluten-free and no artificial flavors
The Key Nutrients of the Supplements are :
Here are key Pros and Cons based on Analysis of Customer Reviews-
- Quick and noticeable improvements for most consumers
- Most consumers experienced no unappealing aftertaste
- Blends easily in liquid intakes
- Easy to use product with convenient packaging
- A few consumers reported inconsistent batch quality and taste
- A few consumers experienced no noticeable impacts on use
Bulksupplements Hydrolyzed Collagen
[amazon fields="B015YG2N22" value="thumb" image_size="large" image_align="center"]Bulk Supplements, based in Nevada, USA is a manufacturer and distributor of dietary supplements, natural products, food and beverages, and cosmetics.
The dietary supplement is available in the form of a powder-mix with net weight 500 g and serving size of 2500 mg. The servings per container amount to 200.
The supplement facts in each serving are:
- Hydrolyzed Collagen
- Sodium
- Protein – 2.2 mg
- Other ingredients include vanilla flavor, gelatin, glycerin, and purified water.
Some of the key USPs of the product are:
- Clean and pure product
- Lab tested for quality assurance
- Factory sealed zip pouch
The Key Nutrients of the Supplements are :
Here are key Pros and Cons based on Analysis of Customer Reviews-
- Quick and noticeable improvements for most consumers
- Most consumers experienced no unappealing aftertaste
- Blends easily in liquid intakes
- Value for money
- A few consumers reported unappealing odor
- A few consumers found the supplement description inadequate
- A few consumers experienced no noticeable impacts on use
Zint Collagen Peptides Powder
[amazon fields="B0722ZP9WK" value="thumb" image_size="large" image_align="center"]Zint Nutrition is a manufacturer and distributor of dietary supplements, superfoods, health and wellness products.
The dietary supplement is available in the form of a powder-mix with net weight 907 g and serving size of 12 g. The servings per container amount to 75.
The supplement facts in each serving are:
- Hydrolyzed beef Collagen
- Protein – 11 g
Some of the key USPs of the product are:
- Premium collagen powder with good dissolvability and taste
- Non-GMO, paleo friendly, kosher and no preservatives
- Collagen type 1 and 3 for easier absorption and effective results
The Key Nutrients of the Supplements are :
Here are key Pros and Cons based on Analysis of Customer Reviews-
- Quick and noticeable improvements for most consumers
- Most consumers experienced no unappealing aftertaste
- Most reported that the ingredients are potent and readily bioavailable
- Blends easily in liquid intakes
- Value for money
- A few consumers reported that scoop addition is required
- A few consumers found the quality, batch size and taste inconsistent
- A few consumers experienced no noticeable impacts on use
Youtheory - Collagen Advanced Formula
[amazon fields="B00U56SLKU" value="thumb" image_size="large" image_align="center"]Youtheory is a manufacturer of nutritional supplements including proteins, probiotics, and collagen.
The dietary supplement consists of 290 tablets with a standard serving size of 6 and servings per container amounting to 48.
The supplement facts in each serving are:
- Collagen blend (1, 2 and 3) – 6000 mg
- Vitamin C – 60 mg
Some of the key USPs of the product are:
- Superior 18 amino acids
- Enhanced joint formula
The Key Nutrients of the Supplements are :
Here are key Pros and Cons based on Analysis of Customer Reviews-
- Quick intended results for most consumers
- Easy to swallow capsules for most consumers
- Most consumers experienced no unappealing aftertaste
- A few consumers experienced no noticeable improvements
- A few consumers experienced difficulty swallowing the capsules
- A few consumers reported that serving size is too large for intended effect
Collagen Wrinkle Formula by Sanar Naturals
[amazon fields="B07C7FS86W" value="thumb" image_size="large" image_align="center"]Sanar Naturals is a manufacturer of nutritional supplements, health and wellness products.
The dietary supplement consists of 150 capsules with a standard serving size of 1 and servings per container amounting to 150.
The supplement facts in each serving are:
- Collagen Hydrolysate and gelatin – 750 mg
- Vitamin C – 90 mg
- Vitamin E
- Other ingredients include magnesium stearate
Some of the key USPs of the product are:
- Tested regularly for quality assurance
- Non-GMO, gluten-free and manufactured in a GMP certified facility
The Key Nutrients of the Supplements are :
Here are key Pros and Cons based on Analysis of Customer Reviews-
- Quick and noticeable improvements for most consumers
- Most consumers experienced no unappealing aftertaste
- Easy to swallow capsules
- Value for money
- A few consumers reported that the product contains unnecessary fillers
- A few consumers found the quality inconsistent
- A few consumers experienced no noticeable impacts on use
Collagen - Structure and Composition
Collagen is made up of containing three polypeptides (α) chains which are held together by hydrogen bonds and are known to have an extended polyproline-II conformation.
It is a right-handed supercoil and has some one-residue stagger between the adjacent chains. [1]
Along with that, every polypeptide chain within the protein has a repeating unit of Gly-X-Y triplet in which the glycyl residues occupy every third position and the X and Y positions are generally occupied by proline and 4-hydroxyproline, respectively. [2][3]
Collagens are known to be the most abundant proteins; they constitute most proteins in mammals. There are have been 26 collagen types found to date. [4]
Out of those 26, five of them are known to occur most frequently. These types are a very necessary part of the body and are found all over the body.
Type 1 Collagen
It is the most abundantly found and the strongest collagen in the body and forms the skin, bones, tendons and other such connective tissues.
Its major source is the supplement containing fish collagen which consists of other amino acids like proline, glycine as well as hydroxyproline.
Another source is egg collagen which contains collagen type 4, type 3 and type 10 in addition to type 1. [5][6]
Type 2 Collagen
It is found in the cartilage which is a connective tissue that protects the bones at the joints. Major sources include supplements containing chicken collagen. [7]
Type 3 Collagen
It is a component of the skin and other organs of the body. It is generally found to be in close association with type 1 collagen and is known to play a role in defining tissue architecture and its mechanical properties. [8]
Its major source is Bovine collagen, which is derived from cows and is also a major source for type 1 collagen. [9]
Type 5 Collagen
It plays a role in the organization and biological properties of the collagenous extracellular matrix. [10]
How Collagen works - Pharmacology
Hydrolysed Collagen has a Dual Mechanism of Action
Firstly, the free amino acids provide building blocks to form collagen and elastin fibers.
Next, the collagen oligopeptides bind to the receptors which are present on the fibroblasts’ membrane and thereby stimulate the production of new collagen, elastin, and hyaluronic acid. [11]
Collagen is also found to reduce the cAMP levels in muscles of the wound, but the concentration of cGMP remains unchanged. Collagen hydrolysate is known to induce unidirectional changes in cyclic nucleotides. [12]
Health benefits of Collagen Supplements
Collagen helps in Keeping the Skin Healthy
Confidence level: High
The amount of collagen produced by the body decreases as the person grows older. This leads to the formation of wrinkles. [13]
A study conducted in 2014 concluded that the oral intake of some specific bioactive collagen peptides reduced wrinkles and increased dermal matrix synthesis. [14]
Another study showed that consuming the oral nutritional supplement of hydrolyzed collagen, hyaluronic acid, and certain essential vitamins and minerals improved the wrinkle depth to a significant degree and also induced hydration to the skin. [15]
Another study showed that oral supplementation of specific peptides of collagen improved skin elasticity and other beneficial effects on human skin physiology. [16]
Some studies on animals have been able to prove the beneficial effects of collagen. [17][18][19]
Other studies on humans have also been able to successfully prove that collagen has been able to improve skin health. [20][21][22][23][24][25][26][27][28]
Collagen helps in Wound Healing
Collagen dressings are known to have chemotactic properties on wound fibroblasts, which encourage the deposition and organization of newly formed collagen, which fosters healing.
Also, collagen-based biomaterials moisturize and stimulate and recruit a few specific cells, such as macrophages and fibroblasts to enhance and influence wound healing.
Confidence level: High
Collagen is a key component in healing. A study proved that collagen sheets are useful in first and second-degree burns. The pain as well the cost associated is drastically reduced. [29]
Another study proved that the process of skin grafting may be avoided completely. In addition to that, it also provided patient comfort and compliance. [30]
Another study has also proved the effectiveness of collagen-nanoparticles for wound healing and controlling the infection. [31]
There have been other studies conducted which prove that collagen is capable of stimulating wound healing by manipulating the wound biochemistry. [32][33][34][35][36][37]
Collagen helps in improving Joint Health
Collagen supplements have been shown to reduce the inflammation as well as stimulate its synthesis within the body. This helps in reducing pain.
Also, collagen is known to naturally contain chondroitin and hyaluronic acid which keep the cartilage healthy and also lubricates joint.
Confidence Level: High
The amount of collagen in the body decreases as one age, the risk of developing joint disorders like arthritis increases. [38]
A study shows that consuming collagen supplements improves symptoms of osteoarthritis and decrease joint pain. [39]
Another 24-week study concluded that consuming collagen hydrolysates as a dietary supplement helped reduce the activity relates to joint pain. [40]
There have been other studies conducted on humans which prove that collagen may help in improving joint help. [41][42][43][44][45][46][47][48][49][50][51][52][53]
Collagen may help boost the Immune System
Collagen may help in seal openings in the gut lining as well as support its integrity. This works in boosting the immune system.
Confidence Level: Moderate
Dendritic cells, which are abundantly found in the intestines can improve immune responses. Collagen may improve primary immune responses as well as the adaptive properties of the immune system. [54]
A study on mice also proved that collagen reduces proinflammatory cytokine production in mice. [55]
Another study on humans proved that individuals with inflammatory bowel disease found that they were likely to have lesser levels of collagen. [56]
Collagen may Promote Heart Health
Confidence Level: Moderate
A six-month study on human adults has proved that consuming collagen daily significantly reduced artery stiffness.
Apart from this, an 6% increase in the level of HDL has also been observed. This might reduce the risk of heart conditions. [57]
Other studies on humans have proved that collagen has been successfully employed to promote heart health. [58] [59]
Collagen may help in Combating Infections
Fish collagen is known to contain collagencin which contains anti-bacterial properties.
Confidence Level: Low
One study has shown have been p that collagencin has completely inhibited the growth of Staphylococcus aureus, which causes Staph infection. [60]
Another study compared the inhibitory activities of Collagen on certain strains of bacteria like Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, Bacillus subtilis, Enterobacter acrogens, Candida albicans.
Out of all the bacteria studied, the growth of S. aureus was affected the most. [61]
There are a few other studies that prove the antibacterial properties of collagen. [62][63][64]
However, none of these studies has been performed on humans and therefore more evidence is required.
Collagen may help to Boost Muscle Mass
Consuming collagen may promote the synthesis of muscle proteins such as creatine and may also stimulate muscle growth.
Confidence Level: low
About 1-10% of the muscle tissue is composed of collagen and therefore it plays a significant role in keeping the muscles strong and functioning properly. [65]
In a 12-week study, some elderly sarcopenic men were administered 15 grams of collagen in combination with resistance training. It was observed that these men gained more muscle mass and strength. [66]
Collagen may help in Preventing bone Loss
Confidence Level: Low
One study conducted in 2013 showed that fish collagen peptides had a positive impact on collagen synthesis and quality. It proved to be helpful in matrix demineralization of bone-synthesizing cells in vitro. [67]
Another study also showed that collagen peptide supplementation exerts a positive effect on osteoblastic cells, which suggests the potential utility for its use in tissue engineering. [68]
However, further studies have to be carried out on humans, before drawing more conclusions.
Side Effects and Safety
Some people have experienced certain side effects like stomach problems, headache, dizziness, difficulty while sleeping, and liver problems.
Dosing
The appropriate dose of collagen relies on the consumer’s age, health, and other factors. There is not enough scientific information available to determine an appropriate range of doses.
Therefore, it is recommended to consult a physician or follow the instructions on the label before use.[69]
Precautions
Pregnancy and Breastfeeding
There is not enough evidence available regarding the consumption of collagen by women who are pregnant or breastfeeding. Therefore, it is recommended to stay on the safe side and avoid its usage or consult a physician before use.
Egg or Chicken Allergies
People allergic to chicken or eggs should avoid the use of collagen type 2, as collagen products have been associated with some allergies.
Interactions
There is not much information available about the interactions of collagen. Therefore, it is better to consult a physician before use.
Overdose
Sufficient evidence is not available about the potential effects of overdosing.
Empty Stomach
There is no sufficient evidence available on whether Chlorophyll can be consumed on an empty stomach or not. It is recommended to read the Bottle label or consult the physician for the same.
FAQs
Some side effects of taking hibiscus might be stomach pain or upset, constipation, decrease in blood sugar levels, headache, nausea, a kind of shakiness feel, and painful urination.
Generally, it is known that free radicals would be harmful to the kidneys. Hibiscus tea is known to provide antioxidant effects thus it helps in the restoration of damaged kidneys. It appears to be very effective and safe and helps maintain the complete urinary tract.
Hibiscus tea is known to have a low content of calories in it and also considered as a naturally caffeine-free supplement.
Hibiscus oil is considered to be very effective in boosting the growth of the hair. It seems to be rich in vitamin C and boosts the production of collagen by giving a healthy condition for your hair. The hibiscus flowers are considered to give long and shiny hair.
Only the data are available for the plant extract but the detailed information of the hibiscus tea on the hair growth is not clearly understood and research is not available much.
The plant works as a diuretic naturally and it helps in the prevention of getting rid of potassium levels in the bod
It is found that hibiscus tea could lower depression. The Hibiscus plant is known to have the antidepressant property in them and thus effectively acts against depression. It gives one's self to experience a calm state of mind and body and thus helping an individual to lower the uncontrolled depression and the feel of anxiety in them.
The nutritional constituents in 100gram of hibiscus tea have 2g of protein, 10.2g of carbohydrates, 0.1g of fat, 0.05g of thiamine, 0.07g of riboflavin, 0.06g of niacin, 17g of vitamin C, 150g of calcium and 3g of iron in it.
Final Words
Collagen is a family of triple helical proteins that is known to have functions associated with tissue scaffolding, cell adhesion, repair, etc. Collagen helps in speedy recovery of wounds, keeping the skin healthy, and improving joint health.
It may also help in improving heart health, combating infections, and boosting muscle mass.