Vitamins play an important role in promoting good health and keeping diseases at bay. They are important for regulating several metabolic processes.
Although a balanced and healthy diet contains essential vitamins, as we age our body undergoes drastic hormonal changes that make it require certain vitamins and nutrients more than before. 
Thus, aged people are more vulnerable to developing disorders associated with multivitamin deficiencies if not present in the diet adequately.
Men and women have different vitamin requirements.
Multivitamin deficiency is known to affect the functioning of the reproductive system, eyes, nervous system, and red blood cell production.
It can give rise to osteoporosis, anemia and autoimmune disorders.
In elderly men, multivitamin deficiencies can increase the risk of heart diseases, arthritis, neurodegenerative disorders, and poor reproductive health.
Best Multivitamins for Men over 50
This section enlists the best vitamin supplements essential for men over 50 to overcome multivitamin deficiency and its associated disorders.
Multivitamin supplements are widely available in the market to address deficiencies and each one of them has a unique role to play in the body.
Vitamin D deficiency is common in aged men.
Aging reduces the efficiency of the skin to synthesize Vitamin D on exposure to sunlight and older people are often likely to stay indoors thereby lacking in sun exposure.
Vitamin D supplements help restore low testosterone levels to normal, maintain bone health, memory and cognition and heart diseases making it a significant vitamin for consumption by men over 50.
Benefit Confidence: High
Vitamin D, popularly known as the sunshine vitamin is unique as it is made by the skin on exposure to sunlight.
Inadequate Vitamin D is known to affect the absorption of other essential nutrients like Calcium and phosphorus and can result in chronic diseases. 
Multiple studies have proven that Vitamin D increases testosterone levels in men.
A clinical study conducted by Pilz et al. in 2011 reported that consumption of Vitamin D supplements by men for a period of 1 year significantly increased the total, bioactive and free testosterone levels. 
Vitamin D protects the heart. According to a clinical study conducted by Framingham, patients with low Vitamin D concentrations were at a 60% higher risk of heart diseases like hypertension as compared to individuals with stable Vitamin D concentrations. 
It strengthens bone health and prevents osteoarthritis. Research studies report that Vitamin D helps the body absorb calcium which is necessary for maintaining the bone health.
Hence insufficient amounts of Vitamin D can increase the risk of fractures and falls or even osteoarthritis. 
Vitamin D reduces the risk of cognitive decline in the elderly making it an essential dietary supplement to protect cognitive health in men over 50. 
Vitamin B6 depletion is a major cause of concern in the elderly. Vitamin B6 supplements help prevent heart diseases, inflammation, cancer and improve cognitive health.
Benefit Confidence: High
Vitamin B6 is a water-soluble vitamin. It is naturally present in the foods and is available as a dietary supplement.
It is easily absorbed by the body even in high doses and being water-soluble is excreted in the urine.
Thus, it is important to keep Vitamin B6 levels stable to meet body requirements. 
Research studies reveal that Elderly men often face rapid Vitamin B6 depletion thereby requiring dietary supplements to meet the body’s requirements. 
Besides, they indicate the necessity of Vitamin B6 as a dietary supplement as low levels of the vitamin is known to increase risks of cardiovascular diseases, inflammatory diseases, and cancer. 
Friso et al. conducted a study in 2012 and reported that there exists a strong correlation between Vitamin B6 and heart health.
The study showed that deficiency of the vitamin resulted in an increased risk of cardiovascular disease. 
Another research study published in The British Journal of Nutrition in 2011 reported the potential of Vitamin B6 to prevent inflammation-related diseases like rheumatoid arthritis and chronic inflammatory bowel diseases when its normal levels are maintained in the body. 
According to a study conducted by Malouf and Evans in 2003, Vitamin B6 was found to significantly reduce blood homocysteine levels thereby preventing the risk of cognitive impairment and dementia in the elderly.
Vitamin B12 is essential in elderly men. It is reported to prevent risks of neurological dysfunction and dementia, it protects heart health and reproductive health by improving the semen quality and regulating hormones.
It fights harmful inflammation and oxidative damage.
Benefit Confidence- High
Vitamin B12, also called Cobalamin, performs vital functions of the body which include red blood cell production, neurological functions, synthesis of DNA and a cofactor for various essential enzymes.
Like Vitamin B6 it is also a water-soluble vitamin. 
Thus, it is highly essential to consume foods and sometimes even dietary supplements to make sure its levels are maintained in the body.
According to researchers, men are more susceptible to Vitamin B12 deficiency as compared to women. 
A recent research study published in Biomolecules reported that Vitamin B12 is found to improve semen quality in men by improving the functioning of the reproductive organs, reducing homocysteine toxicity, nitric oxide generation, inflammation and oxidative damage to sperms.
Other studies support the findings indicating the possible role of Vitamin B12 in spermatogenesis in men. 
Vitamin B12 deficiency is known to affect hematological, cardiovascular and neurological functions. 
Vitamin B12 is involved in the metabolism of homocysteine.
According to a research study published in The Journal of International medicine in 2003, Vitamin B12 maintains cognitive function and reduces the risk of dementia in the elderly.
Folic acid deficiency is very uncommon. However, Vitamin supplements are known to play in role in vital functions like reducing the toxicity of certain drugs, preventing depression, autism and improving the health of the neurons.
Vitamin B9 also plays a role in preventing erectile dysfunction and promoting the health of the reproductive system.
Benefit confidence- High
Vitamin B9, commonly known as folate or folic acid is an important B vitamin responsible for healthy cell growth and metabolism.
Its deficiency can result in anemia amongst other impairments.
It is common in people suffering from malfunctioning of the liver and kidney, alcohol addiction and digestive problems.
Folate is commonly prescribed to reduce the toxicity of drugs like methotrexate used in psoriasis and arthritis. 
Folate deficiency is not very common and occurs only in cases of poor diet, alcoholism or malabsorption.
Folate has found to beneficial in mitigating neurological disorders like Autism and depression.
The possible mechanism of action has been found to be its key role in homocysteine metabolism and neurotransmitter synthesis.
A research study conducted by Karabakan et al. reported the association of Folate deficiency with erectile dysfunction.
Vitamin C is an important vitamin and dietary supplements can help improve sperm quality and overall reproductive health, it can also prevent the risk of gout and a highly efficient and safe pain reliever.
Benefit Confidence- Medium
Vitamin C is an essential vitamin as it is a significant anti-oxidant, repairs tissue, skin and bone damage. It promotes healing and also aids in the absorption of iron. 
Elderly men are at an increased risk of Gout, a form of arthritis due to high uric acid levels.
Researchers have reported the potential role of Vitamin C supplements as a therapy for acute and chronic pain suffered during arthritis.
It is also found to relieve musculoskeletal, neuropathic and nociceptive pain. Vitamin C is regarded as a safe and effective pain killer. 
Vitamin C is also known to reduce the risk of cancers. 
The Vitamins mentioned do not interact with one another however they may interact with medications resulting in adverse side effects.
It is recommended to keep large gaps between consuming multivitamins and medications and consult a health practitioner to identify safety and prevent undesirable interactions.
Multivitamins help ensure good health and protect from age-related diseases associated with the heart, reproductive organs, and the brain.
Vitamin C, B12, B9, B6, and Vitamin D are playing a significant role in protecting age-related complications in men who are deficient in these vitamins.